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QP5

Catalog No.: A95077
Amelogenin-derived Peptide
QP5 is an amelogenin-derived peptide that targets hydroxyapatite and demineralized tooth enamel surfaces. It transiently stabilizes amorphous calcium phosphate (ACP), regulates hydroxyapatite crystallization, and promotes remineralization of carious lesions. In rat caries models, QP5 has demonstrated significant efficacy in enhancing remineralization, making it valuable for research in oral diseases such as dental caries.
QP5 1501983-51-2 Amelogenin-derived Peptide
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Size Price Stock Qty
1mg
$50.00
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5mg
$125.00
In stock
10mg
$200.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionQP5 is an amelogenin-derived peptide that targets hydroxyapatite and demineralized tooth enamel surfaces. It transiently stabilizes amorphous calcium phosphate (ACP), regulates hydroxyapatite crystallization, and promotes remineralization of carious lesions. In rat caries models, QP5 has demonstrated significant efficacy in enhancing remineralization, making it valuable for research in oral diseases such as dental caries.
Product Information
Catalog NumA95077
FormulaC115H178N34O37S
Molecular Weight2660.91
CAS Number1501983-51-2
SequenceGln-Pro-Tyr-Gln-Pro-Val-Gln-Pro-His-Gln-Pro-Met-Gln-Pro-Gln-Thr-Lys-Arg-Glu-Glu-Val-Asp
Sequence shorteningQPYQPVQPHQPMQPQTKREEVD
SMILESC(N[C@@H](CC1=CN=CN1)C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(O)=O)=O)[C@H](C)C)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)[C@@H](C)O)=O)CCC(N)=O)=O)CCC3)CCC(N)=O)=O)CCSC)=O)CCC2)CCC(N)=O)=O)(=O)[C@H]4N(C([C@@H](NC([C@@H](NC(=O)[C@H]5N(C([C@@H](NC([C@@H](NC(=O)[C@H]6N(C([C@H](CCC(N)=O)N)=O)CCC6)CC7=CC=C(O)C=C7)=O)CCC(N)=O)=O)CCC5)C(C)C)=O)CCC(N)=O)=O)CCC4
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