Quinolinic acid-13C7 is a stable isotope-labeled form of quinolinic acid, an endogenous metabolite of tryptophan. This compound acts as an N-methyl-D-aspartate (NMDA) receptor agonist, enhancing glutamate release, promoting reactive oxygen species generation, and activating nitric oxide synthase. These actions can lead to increased nitric oxide production, calcium ion influx, and consequent neuronal apoptosis, making this reagent valuable for studies in neurobiology, metabolism, and neurodegenerative diseases.
Quinolinic acid-13C7 is a stable isotope-labeled form of quinolinic acid, an endogenous metabolite of tryptophan. This compound acts as an N-methyl-D-aspartate (NMDA) receptor agonist, enhancing glutamate release, promoting reactive oxygen species generation, and activating nitric oxide synthase. These actions can lead to increased nitric oxide production, calcium ion influx, and consequent neuronal apoptosis, making this reagent valuable for studies in neurobiology, metabolism, and neurodegenerative diseases.
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