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R-10015, a broad-spectrum antiviral compound for HIV infection, acts as a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket, with an IC50 of 38 nM for human LIMK1.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.34 mL | 121.7 mL | 243.39 mL |
| 0.5 mM | 4.87 mL | 24.34 mL | 48.68 mL |
| 1 mM | 2.43 mL | 12.17 mL | 24.34 mL |
| 5 mM | 0.49 mL | 2.43 mL | 4.87 mL |
*The above data is based on the productmolecular weight 410.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18806 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 410.86 |
| Formula | C20H19ClN6O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2097938-51-5 |
| Synonyms | R10015, R 10015 |
| SMILES | O=C(C1=CC=C2NC(C3CCN(C4=C5C(NC=C5Cl)=NC=N4)CC3)=NC2=C1)OC |
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