(R)-Avanafil

Catalog No.: A42136
PDE5 Inhibitor
(R)-Avanafil is a potent and selective inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 5.2 nM. This compound is utilized in research pertaining to erectile dysfunction, offering insights into its pharmacological effects and potential therapeutic applications. Its specificity for PDE5 makes it a valuable tool for studying the modulation of cyclic nucleotide signaling pathways.
Grouped product items
Size Price Stock Qty
5mg
$550.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(R)-Avanafil is a potent and selective inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 5.2 nM. This compound is utilized in research pertaining to erectile dysfunction, offering insights into its pharmacological effects and potential therapeutic applications. Its specificity for PDE5 makes it a valuable tool for studying the modulation of cyclic nucleotide signaling pathways.
Product Information
Catalog NumA42136
FormulaC23H26ClN7O3
Molecular Weight483.95
CAS Number1638497-26-3
SMILESCOC1=C(Cl)C=C(CNC2=C(C(NCC3=NC=CC=N3)=O)C=NC(N4[C@@H](CO)CCC4)=N2)C=C1
Synonyms(R)-TA1790
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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