(R)-BAY1238097

Catalog No.: A21593

BET binding to histones inhibitor

(R)-BAY1238097

(R)-BAY1238097 Chemical Structure

CAS NO. 1564269-85-7

(R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple myeloma) models through down-regulation of c-Myc levels and its downstream transcriptome.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $225.00

Special Price $180.00

10 mg

Regular Price: $388.00

Special Price $310.40

50 mg

Regular Price: $1,150.00

Special Price $920.00

100 mg

Regular Price: $2,300.00

Special Price $1,840.00

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Biological Activity

(R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple myeloma) models through down-regulation of c-Myc levels and its downstream transcriptome.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.15 mL 110.73 mL 221.45 mL
0.5 mM 4.43 mL 22.15 mL 44.29 mL
1 mM 2.21 mL 11.07 mL 22.15 mL
5 mM 0.44 mL 2.21 mL 4.43 mL

*The above data is based on the productmolecular weight 451.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21593
Actions Inhibitor
CAS No. 1564269-85-7
Formula C25H33N5O3
M. Wt 451.56
Purity >98%
Synonyms BAY 1238097, BAY1238097
SMILES O=C(N1N=C(C2=CC=C(N3CCN(C)CC3)C=C2)C4=CC(OC)=C(OC)C=C4C[[email protected]]1C)NC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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