(R)-Bromoenol lactone is an irreversible chiral inhibitor targeting calcium-independent phospholipase γ (iPLA2γ). It exhibits potent inhibition of human recombinant iPLA2γ, with an IC50 value of approximately 0.6 µM. This compound is significant for research applications involving lipid signaling, inflammatory responses, and cellular metabolism.
(R)-Bromoenol lactone is an irreversible chiral inhibitor targeting calcium-independent phospholipase γ (iPLA2γ). It exhibits potent inhibition of human recombinant iPLA2γ, with an IC50 value of approximately 0.6 µM. This compound is significant for research applications involving lipid signaling, inflammatory responses, and cellular metabolism.
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