(R)-CE3F4

Catalog No.: A21358

exchange protein inhibitor

(R)-CE3F4

(R)-CE3F4 Chemical Structure

CAS NO. 1593478-56-8

(R)-CE3F4 is a potent and selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1), with an IC50 of 4.2 μM, with 10-fold selectivity for Epac1 over Epac2 (IC50, 44 μM).

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

(R)-CE3F4 is a potent and selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1), with an IC50 of 4.2 μM, with 10-fold selectivity for Epac1 over Epac2 (IC50, 44 μM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.49 mL 142.45 mL 284.89 mL
0.5 mM 5.7 mL 28.49 mL 56.98 mL
1 mM 2.85 mL 14.24 mL 28.49 mL
5 mM 0.57 mL 2.85 mL 5.7 mL

*The above data is based on the productmolecular weight 351.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21358
Actions Inhibitor
CAS No. 1593478-56-8
Formula C11H10Br2FNO
M. Wt 351.01
Solubility DMSO
Purity >98%
SMILES O=CN1[[email protected]](C)CCC2=C1C=C(Br)C(F)=C2Br
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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