(R)-DNMDP is a selective phosphodiesterase 3A (PDE3A) inhibitor, demonstrating significant cytotoxic effects on cancer cells. This compound binds directly to PDE3A, exhibiting a remarkable 500-fold lower EC50 in the HeLa cell line compared to its (S)-enantiomer. Its potent biological activity makes (R)-DNMDP a valuable tool for research related to cancer therapeutics and the modulation of cellular signaling pathways.
(R)-DNMDP is a selective phosphodiesterase 3A (PDE3A) inhibitor, demonstrating significant cytotoxic effects on cancer cells. This compound binds directly to PDE3A, exhibiting a remarkable 500-fold lower EC50 in the HeLa cell line compared to its (S)-enantiomer. Its potent biological activity makes (R)-DNMDP a valuable tool for research related to cancer therapeutics and the modulation of cellular signaling pathways.
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