(R)-eIF4A3-IN-2 is the less active enantiomer of eIF4A3-IN-2, a selective noncompetitive inhibitor of eukaryotic initiation factor 4A-3 (eIF4A3). With an IC50 of 110 nM, eIF4A3-IN-2 demonstrates significant inhibition of eIF4A3, impacting mRNA splicing and translation processes. This compound is useful in research applications focused on cancer biology, novel therapeutic pathways, and the regulation of gene expression.
(R)-eIF4A3-IN-2 is the less active enantiomer of eIF4A3-IN-2, a selective noncompetitive inhibitor of eukaryotic initiation factor 4A-3 (eIF4A3). With an IC50 of 110 nM, eIF4A3-IN-2 demonstrates significant inhibition of eIF4A3, impacting mRNA splicing and translation processes. This compound is useful in research applications focused on cancer biology, novel therapeutic pathways, and the regulation of gene expression.
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