(R)-IDO/TDO-IN-1 is an indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor. It demonstrates notable anti-tumor activity in the MC38 xenograft model and exhibits synergistic effects when combined with anti-PD-1 monoclonal antibodies, such as SHR-1210. This compound is applicable in cancer research, particularly in studying immune modulation and therapeutic strategies targeting the kynurenine pathway.
(R)-IDO/TDO-IN-1 is an indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor. It demonstrates notable anti-tumor activity in the MC38 xenograft model and exhibits synergistic effects when combined with anti-PD-1 monoclonal antibodies, such as SHR-1210. This compound is applicable in cancer research, particularly in studying immune modulation and therapeutic strategies targeting the kynurenine pathway.
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