(R)-(-)-Rolipram is a selective inhibitor of phosphodiesterase 4 (PDE4), demonstrating IC50 values of 3 nM, 130 nM, and 240 nM for PDE4A, PDE4B, and PDE4D, respectively. This compound enhances intracellular cAMP levels, making it a valuable tool for studying signal transduction pathways. It is commonly utilized in research related to neuroprotection, inflammation, and other disorders linked to dysregulated cAMP signaling.
(R)-(-)-Rolipram is a selective inhibitor of phosphodiesterase 4 (PDE4), demonstrating IC50 values of 3 nM, 130 nM, and 240 nM for PDE4A, PDE4B, and PDE4D, respectively. This compound enhances intracellular cAMP levels, making it a valuable tool for studying signal transduction pathways. It is commonly utilized in research related to neuroprotection, inflammation, and other disorders linked to dysregulated cAMP signaling.
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