Biological Activity
(R)-Simurosertib ((R)-TAK-931) is the (R)-enantiomer of Simurosertib, Simurosertib (TAK-931) is a selective cycle 7 (CDC7) kinase inhibitor, with an IC50<0.3 nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 29.29 mL | 146.44 mL | 292.89 mL |
0.5 mM | 5.86 mL | 29.29 mL | 58.58 mL |
1 mM | 2.93 mL | 14.64 mL | 29.29 mL |
5 mM | 0.59 mL | 2.93 mL | 5.86 mL |
*The above data is based on the productmolecular weight 341.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A21894 |
---|---|
Actions | Inhibitor |
CAS No. | 1330782-69-8 |
Formula | C17H19N5OS |
M. Wt | 341.43 |
Purity | >98% |
Synonyms | (R)-TAK-931, TAK931, TAK 931 |
SMILES | O=C(C1=C(N2)C=C(C3=CNN=C3C)S1)N=C2[[email protected]]4CC5CCN4CC5 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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