Fig. 1 · Structure
Documents & Downloads
(R)-(+)-Verapamil-d6 hydrochloride
Stable Isotope
(R)-(+)-Verapamil-d6 hydrochloride is a deuterium-labeled derivative of (R)-Verapamil hydrochloride, serving as a stable isotope. This compound primarily functions as a P-glycoprotein inhibitor and effectively blocks MRP1-mediated transport. Its biological activity makes it a valuable tool for research in chemosensitization of MRP1-overexpressing cells to various anticancer agents, enhancing the understanding of drug resistance mechanisms in cancer therapy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1795786-09-2 |
| Applications | Stable Isotope |
| Formula | C27H33D6ClN2O4 |
| Molecular Weight | 497.10 |
| SMILES | COC1=C(C=CC(CCN(CCC[C@](C#N)(C2=CC=C(C(OC)=C2)OC)C(C([2H])([2H])[2H])C([2H])([2H])[2H])C)=C1)OC.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.