(R)-(+)-Verapamil-d6 hydrochloride is a deuterium-labeled derivative of (R)-Verapamil hydrochloride, serving as a stable isotope. This compound primarily functions as a P-glycoprotein inhibitor and effectively blocks MRP1-mediated transport. Its biological activity makes it a valuable tool for research in chemosensitization of MRP1-overexpressing cells to various anticancer agents, enhancing the understanding of drug resistance mechanisms in cancer therapy.
(R)-(+)-Verapamil-d6 hydrochloride is a deuterium-labeled derivative of (R)-Verapamil hydrochloride, serving as a stable isotope. This compound primarily functions as a P-glycoprotein inhibitor and effectively blocks MRP1-mediated transport. Its biological activity makes it a valuable tool for research in chemosensitization of MRP1-overexpressing cells to various anticancer agents, enhancing the understanding of drug resistance mechanisms in cancer therapy.
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