(R)-Zadavotide guraxetan

Catalog No.: A65461
PSMA Inhibitor
(R)-Zadavotide guraxetan is a potent inhibitor of prostate-specific membrane antigen (PSMA), exhibiting significant antitumor activity. It is primarily utilized in research focused on prostate cancer, contributing to the understanding of targeted therapeutic approaches. This compound serves as a valuable tool for investigating the role of PSMA in cancer biology and evaluating efficacy in preclinical studies.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(R)-Zadavotide guraxetan is a potent inhibitor of prostate-specific membrane antigen (PSMA), exhibiting significant antitumor activity. It is primarily utilized in research focused on prostate cancer, contributing to the understanding of targeted therapeutic approaches. This compound serves as a valuable tool for investigating the role of PSMA in cancer biology and evaluating efficacy in preclinical studies.
Product Information
Catalog NumA65461
FormulaC63H92IN11O23
Molecular Weight1498.37
CAS Number2647371-60-4
Sequence(R)-DOTA-{3-I-dTyr}-{dPhe}-{dLys-C8 diacid-eLys}-Glu
Sequence shortening(R)-DOTA-{3-I-dTyr}-{dPhe}-{dLys-C8 diacid-eLys}-E
SMILES[C@@H](CCC(N[C@H](CC1=CC(I)=C(O)C=C1)C(N[C@H](CC2=CC=CC=C2)C(N[C@H](CCCCNC(CCCCCCC(NCCCC[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=O)C(O)=O)=O)=O)C(O)=O)=O)=O)=O)(C(O)=O)N3CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC3
Synonyms(R)-PSMA I&T; (R)-PNT-2002
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