Biological Activity
R18, antagonist of 14.3.3 proteins (KD ≈ 80 nM). Competitively inhibits 14.3.3-ligand interactions without requiring phosphorylation.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 4.33 mL | 21.65 mL | 43.3 mL |
0.5 mM | 0.87 mL | 4.33 mL | 8.66 mL |
1 mM | 0.43 mL | 2.16 mL | 4.33 mL |
5 mM | 0.09 mL | 0.43 mL | 0.87 mL |
*The above data is based on the productmolecular weight 2309.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15329 |
---|---|
Actions | Antagonist |
M. Wt | 2309.69 |
Formula | C101H157N27O29S3 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 211364-78-2 |
Synonyms | R 18, R-18 |
SMILES | CC(C)CC(C(=O)NC(CC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CC(=O)N)C(=O)NC(CCSC)C(=O)NC(CS)C(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)O)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C4CCCN4C(=O)C(C(C)C)N |
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