R406 (Tamatinib)

Catalog No.: A10770

Syk Inhibitor

R406 (Tamatinib)

R406 (Tamatinib) Chemical Structure

CAS NO. 841290-80-0

R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.

Availability: In stock

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10 mg

Regular Price: $150.00

Special Price $120.00

25 mg

Regular Price: $280.00

Special Price $224.00

50 mg

Regular Price: $500.00

Special Price $400.00

100 mg

Regular Price: $880.00

Special Price $704.00

10mM * 1mL in DMSO

Regular Price: $130.00

Special Price $104.00

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Biological Activity

R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.
Syk (Cell-free assay)
41 nM
In vitro (25°C) DMSO 18 mg/mL (38.25 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.25 mL 106.27 mL 212.54 mL
0.5 mM 4.25 mL 21.25 mL 42.51 mL
1 mM 2.13 mL 10.63 mL 21.25 mL
5 mM 0.43 mL 2.13 mL 4.25 mL

*The above data is based on the productmolecular weight 470.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10770
Actions Inhibitor
CAS No. 841290-80-0
Formula C22H23FN6O5
M. Wt 470.5
Purity >98%
Synonyms R-406

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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