R406 (Tamatinib)

Catalog No.: A10770
Syk Inhibitor
R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.
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Product Name Price Stock Qty
R406 (freebase) 10mg
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R406 (freebase) 25mg
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R406 (freebase) 50mg
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R406 (freebase) 100mg
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R406 (freebase) 10mM * 1mL in DMSO
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Biological Activity
Discription R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.
Target Value
Product Information
Catalog Num A10770
Formula C22H23FN6O5
Molecular Weight 470.5
CAS Number 841290-80-0
Synonyms R-406

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro (25°C) DMSO 18 mg/mL (38.25 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.25 mL 106.27 mL 212.54 mL
0.5 mM 4.25 mL 21.25 mL 42.51 mL
1 mM 2.13 mL 10.63 mL 21.25 mL
5 mM 0.43 mL 2.13 mL 4.25 mL
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Calculate the dilution required to prepare a stock solution.
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