R406 besylate

Name: R406 besylate
SKU: A10769
Price: 35 USD
Rating: 5 (2 reviews)

Catalog No.: A10769

Syk Inhibitor

Adooq's R406 besylate has been cited by 2 publications

R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
Size	Price	Stock
1mg	$35.00	In stock
2mg	$45.00	In stock
5mg	$80.00	In stock
10mg	$145.00	In stock
25mg	$325.00	In stock
50mg	$490.00	In stock
100mg	$710.00	In stock
*10mM 1mL in DMSO**	$120.00	In stock
Bulk Size	Bulk Discount

Bulk Inquiry

Notify me when the price drops

Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

Other Forms of R406 besylate

R406 (Tamatinib)

Adooq Products cited in reputable paper

Adooq's R406 besylate has been cited by 2 publications

Sina Ghasempour, .et al. , J Immunol, 2024, Oct 1;213(7):988-997 PMID: 39140892

Gabriella Leung, .et al. , JCI insight, 2021, Dec 8;6(23):e149376 PMID: 34673575

Biological Activity

Discription

R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.

Targets

Target	Value

Product Information

Catalog Num	A10769
Formula	C22H23FN6O5.C6H6O3S
Molecular Weight	628.6
CAS Number	841290-81-1
SMILES	CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)O
Synonyms	R-406
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	92 mg/mL (146.34 mM)
	Water	Insoluble
	In vivo	5%dmso+95%cornoil	5 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.91 mL	79.54 mL	159.08 mL
0.5 mM	3.18 mL	15.91 mL	31.82 mL
1 mM	1.59 mL	7.95 mL	15.91 mL
5 mM	0.32 mL	1.59 mL	3.18 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂