R406 besylate

Name: R406 besylate
SKU: A10769
Price: 50 USD
Rating: 5 (1 reviews)

Catalog No.: A10769

Syk Inhibitor

Adooq's R406 besylate has been cited by 1 publications

R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

Other Forms of R406 besylate

R406 (Tamatinib)

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Adooq Products cited in reputable paper

Adooq's R406 besylate has been cited by 1 publications

Gabriella Leung, .et al. , JCI insight, 2021, Dec 8;6(23):e149376 PMID: 34673575

Biological Activity

Discription

R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.

Targets

Target	Value

Chemical Information

Catalog Num	A10769
Formula	C22H23FN6O5.C6H6O3S
Molecular Weight	628.6
CAS Number	841290-81-1
SMILES	CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)O
Synonyms	R-406
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	92 mg/mL (146.34 mM)
	Water	Insoluble
	In vivo	5%dmso+95%cornoil	5 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.91 mL	79.54 mL	159.08 mL
0.5 mM	3.18 mL	15.91 mL	31.82 mL
1 mM	1.59 mL	7.95 mL	15.91 mL
5 mM	0.32 mL	1.59 mL	3.18 mL

Useful Calculator

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Product Name	Price	Stock
R406 2mg	$50.00	In stock
R406 5mg	$100.00	In stock
R406 10mg	$150.00	In stock
R406 50mg	$500.00	In stock
*R406 10mM 1mL in DMSO**	$373.00	In stock