R406 besylate

Catalog No.: A10769
Syk Inhibitor
R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.
Grouped product items
Product Name Price Stock Qty
R406 2mg
In stock
R406 5mg
In stock
R406 10mg
In stock
R406 50mg
In stock
R406 10mM * 1mL in DMSO
In stock

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's R406 besylate has been cited by 1 publications
  • Gabriella Leung, .et al. , JCI insight, 2021, Dec 8;6(23):e149376 PMID: 34673575
  • Biological Activity
    Discription R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.
    Target Value
    Chemical Information
    Catalog Num A10769
    Formula C22H23FN6O5.C6H6O3S
    Molecular Weight 628.6
    CAS Number 841290-81-1
    SMILES CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)O
    Synonyms R-406

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 92 mg/mL (146.34 mM)
    Water Insoluble
    In vivo 5%dmso+95%cornoil 5 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 15.91 mL 79.54 mL 159.08 mL
    0.5 mM 3.18 mL 15.91 mL 31.82 mL
    1 mM 1.59 mL 7.95 mL 15.91 mL
    5 mM 0.32 mL 1.59 mL 3.18 mL
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