R788 (Fostamatinib)

Catalog No.: A11926

Syk inhibitor

R788 (Fostamatinib)

R788 (Fostamatinib) Chemical Structure

CAS NO. 901119-35-5

R788 (Fostamatinib) is an important spleen tyrosine kinase (Syk) inhibitor, showing efficacy against kinase-mediated IgG Fc gamma receptor signaling.

Availability: In stock

Package Price Qty
2 mg

Regular Price: $60.00

Special Price $54.00

5 mg

Regular Price: $100.00

Special Price $90.00

10 mg

Regular Price: $180.00

Special Price $162.00

25 mg

Regular Price: $400.00

Special Price $360.00

10mM * 1mL in DMSO

Regular Price: $233.00

Special Price $209.70

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

R788 (Fostamatinib) is an important spleen tyrosine kinase (Syk) inhibitor, showing efficacy against kinase-mediated IgG Fc gamma receptor signaling.
Targets
Syk Adenosine A3 receptor Adenosine transporter Monoamine transporter
41 nM81 nM1.84 μM2.74 μM
In vitro (25°C) DMSO 116 mg/mL (199.84 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.23 mL 86.13 mL 172.27 mL
0.5 mM 3.45 mL 17.23 mL 34.45 mL
1 mM 1.72 mL 8.61 mL 17.23 mL
5 mM 0.34 mL 1.72 mL 3.45 mL

*The above data is based on the productmolecular weight 580.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A11926
Actions Inhibitor
M. Wt 580.5
Formula C23H26FN6O9P
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 901119-35-5
Synonyms R-788
SMILES CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)(O)O)C

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