R788 (Fostamatinib)

R788 (Fostamatinib) is an important spleen tyrosine kinase (Syk) inhibitor, showing efficacy against kinase-mediated IgG Fc gamma receptor signaling.
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R788 2mg
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R788 5mg
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R788 10mg
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R788 25mg
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R788 (Fostamatinib) 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's R788 (Fostamatinib) has been cited by 4 publications
  • Mahon OR, .et al. , Acta Biomater, 2018, Jan;65:426-435 PMID: 29104084
  • Emma M. Corr, .et al. , Arthritis Res Ther, 2017, 19: 23 PMID: 28173838
  • Cunningham CC, .et al. , Osteoarthritis Cartilage, 2016, Dec;24(12):2141-2152 PMID: 27426968
  • Corr EM, .et al. , Atherosclerosis, 2016, Aug;251:197-205 PMID: 27356299
  • Biological Activity
    Discription R788 (Fostamatinib) is an important spleen tyrosine kinase (Syk) inhibitor, showing efficacy against kinase-mediated IgG Fc gamma receptor signaling.
    Target Value
    Product Information
    Catalog Num A11926
    Formula C23H26FN6O9P
    Molecular Weight 580.5
    CAS Number 901119-35-5
    SMILES CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)(O)O)C
    Synonyms R-788

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 107 mg/mL (184.34 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 4% DMSO+30% PEG 300+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.23 mL 86.13 mL 172.27 mL
    0.5 mM 3.45 mL 17.23 mL 34.45 mL
    1 mM 1.72 mL 8.61 mL 17.23 mL
    5 mM 0.34 mL 1.72 mL 3.45 mL
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