(Rac)-Dencichine, the racemic form of Dencichin, targets Hypoxia-Inducible Factor (HIF) by inhibiting HIF prolyl-hydroxylase-2 (PHD-2) activity. This non-protein amino acid, derived from Panax notoginseng, exhibits significant biological activity in promoting HIF stabilization under normoxic conditions. Its ability to modulate HIF pathways makes it valuable in research applications related to cancer biology, ischemia, and metabolic regulation.
(Rac)-Dencichine, the racemic form of Dencichin, targets Hypoxia-Inducible Factor (HIF) by inhibiting HIF prolyl-hydroxylase-2 (PHD-2) activity. This non-protein amino acid, derived from Panax notoginseng, exhibits significant biological activity in promoting HIF stabilization under normoxic conditions. Its ability to modulate HIF pathways makes it valuable in research applications related to cancer biology, ischemia, and metabolic regulation.
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