Rac-Pemafibrate is a potent PPARα agonist, effectively activating PPARα with an EC50 of 1 nM, while also showing activity for PPARγ and PPARδ with EC50 values exceeding 10 μM and 1.7 μM, respectively. This racemic compound is essential for research focused on metabolic disorders, lipid metabolism, and inflammation, providing insights into the role of PPARs in these biological pathways. It serves as a valuable tool for studying PPAR-related mechanisms and therapeutic interventions.
Rac-Pemafibrate is a potent PPARα agonist, effectively activating PPARα with an EC50 of 1 nM, while also showing activity for PPARγ and PPARδ with EC50 values exceeding 10 μM and 1.7 μM, respectively. This racemic compound is essential for research focused on metabolic disorders, lipid metabolism, and inflammation, providing insights into the role of PPARs in these biological pathways. It serves as a valuable tool for studying PPAR-related mechanisms and therapeutic interventions.
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