Raf inhibitor 3

Catalog No.: A40732
Raf Inhibitor
Raf Inhibitor 3 specifically targets Raf kinases, including B-Raf and C-Raf, with IC50 values below 15 nM. This compound demonstrates potent inhibitory activity, making it a valuable tool for research focused on oncogenic signaling pathways in cancer. Raf Inhibitor 3 is suitable for studying the role of Raf kinases in tumor biology and evaluating potential therapeutic strategies against Raf-dependent malignancies.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRaf Inhibitor 3 specifically targets Raf kinases, including B-Raf and C-Raf, with IC50 values below 15 nM. This compound demonstrates potent inhibitory activity, making it a valuable tool for research focused on oncogenic signaling pathways in cancer. Raf Inhibitor 3 is suitable for studying the role of Raf kinases in tumor biology and evaluating potential therapeutic strategies against Raf-dependent malignancies.
Product Information
Catalog NumA40732
FormulaC18H19FN8O2S
Molecular Weight430.46
CAS Number1662682-11-2
SMILESO=S(NC1=C(F)C(C2=NN(C(C)C)N=C2C3=CNN=C3)=CC=C1)(C4=CN(C)N=C4)=O
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