RAF mutant-IN-1

Catalog No.: A19011

Raf nhibitor

RAF mutant-IN-1

RAF mutant-IN-1 Chemical Structure

CAS NO. 2340020-82-6

RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF340D/Y341D, B-RAFV600E and B-RAFWT, respectively.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF340D/Y341D, B-RAFV600E and B-RAFWT, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.61 mL 88.05 mL 176.1 mL
0.5 mM 3.52 mL 17.61 mL 35.22 mL
1 mM 1.76 mL 8.81 mL 17.61 mL
5 mM 0.35 mL 1.76 mL 3.52 mL

*The above data is based on the productmolecular weight 567.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19011
Actions Inhibitor
M. Wt 567.85
Formula C23H18Cl3FN6O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2340020-82-6
SMILES O=C(C1=CSC2=C(N)N=CN=C21)NC3=C(C)C=CC4=C3C=CN=C4NC5=CC=C(O)C(Cl)=C5F.[H]Cl.[H]Cl

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