Raloxifene 4'-glucuronide is a major metabolite of Raloxifene that functions as a selective estrogen receptor modulator. It primarily interacts with the estrogen receptor, demonstrating an IC50 of 370 μM. This compound activates the TGFβ3 promoter as a full agonist at nanomolar concentrations while inhibiting expression of the estrogen response element-containing vitellogenin promoter. Raloxifene 4'-glucuronide is useful for research applications in understanding estrogenic activity and signaling pathways.
Raloxifene 4'-glucuronide is a major metabolite of Raloxifene that functions as a selective estrogen receptor modulator. It primarily interacts with the estrogen receptor, demonstrating an IC50 of 370 μM. This compound activates the TGFβ3 promoter as a full agonist at nanomolar concentrations while inhibiting expression of the estrogen response element-containing vitellogenin promoter. Raloxifene 4'-glucuronide is useful for research applications in understanding estrogenic activity and signaling pathways.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
