Neutral Endopeptidase Inhibitor, Aminopeptidase N Inhibitor
RB 101 is a mixed inhibitor of neutral endopeptidase and aminopeptidase N, enzymes that metabolize enkephalins. This compound exhibits long-lasting antinociceptive effects and inhibits in vivo [3H]DPN binding in mice under both basal conditions and after swim stress. RB 101 is particularly useful for studying the in vivo localization of enkephalinergic pathways activated by various stimuli, making it a valuable tool for pain research and neuropharmacology.
RB 101 is a mixed inhibitor of neutral endopeptidase and aminopeptidase N, enzymes that metabolize enkephalins. This compound exhibits long-lasting antinociceptive effects and inhibits in vivo [3H]DPN binding in mice under both basal conditions and after swim stress. RB 101 is particularly useful for studying the in vivo localization of enkephalinergic pathways activated by various stimuli, making it a valuable tool for pain research and neuropharmacology.
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