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Refisolone

Catalog No.: A66773
GABA(A) Receptor Antagonist
Refisolone is a selective antagonist of the GABAA receptor, effectively inhibiting its activity. This compound plays a crucial role in research related to anxiety, sedation, and other neurological disorders by modulating inhibitory neurotransmission. Refisolone is valuable for studying the physiological and pharmacological effects of GABAA receptor modulation in various experimental models.
Refisolone 202718-04-5 GABA(A) Receptor Antagonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRefisolone is a selective antagonist of the GABAA receptor, effectively inhibiting its activity. This compound plays a crucial role in research related to anxiety, sedation, and other neurological disorders by modulating inhibitory neurotransmission. Refisolone is valuable for studying the physiological and pharmacological effects of GABAA receptor modulation in various experimental models.
Product Information
Catalog NumA66773
FormulaC18H24O3
Molecular Weight288.38
CAS Number202718-04-5
SMILESC[C@@]12[C@](C[C@]3([H])[C@@]2([H])O3)([H])[C@@]4([H])[C@]([C@@]5(C(CC4)=CC(CC5)=O)O)([H])CC1
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Neuronal Signaling > GABA Receptors