(rel)-PRT062607 is a selective inhibitor of Syk kinase, demonstrating high potency with an IC50 value of 1-2 nM. This compound exhibits over 80-fold selectivity against related kinases such as Fgr, Lyn, FAK, Pyk2, and Zap70. Its specificity makes it a valuable tool for studying Syk-mediated pathways in various biological contexts and offers potential applications in autoimmune and inflammatory disease research.
(rel)-PRT062607 is a selective inhibitor of Syk kinase, demonstrating high potency with an IC50 value of 1-2 nM. This compound exhibits over 80-fold selectivity against related kinases such as Fgr, Lyn, FAK, Pyk2, and Zap70. Its specificity makes it a valuable tool for studying Syk-mediated pathways in various biological contexts and offers potential applications in autoimmune and inflammatory disease research.
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