RGB-286638

Catalog No.: A13130

CDK inhibitor

RGB-286638

RGB-286638 Chemical Structure

CAS NO. 784210-87-3

RGB-286638 is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively; less potent against cyclin H-CDK7 and cyclin D3-CDK6.

Availability: In stock

Package Price Qty
5 mg
$150.00
10 mg
$250.00
25 mg
$580.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

RGB-286638 is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively; less potent against cyclin H-CDK7 and cyclin D3-CDK6.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.17 mL 80.83 mL 161.67 mL
0.5 mM 3.23 mL 16.17 mL 32.33 mL
1 mM 1.62 mL 8.08 mL 16.17 mL
5 mM 0.32 mL 1.62 mL 3.23 mL

*The above data is based on the productmolecular weight 618.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13130
Actions Inhibitor
M. Wt 618.55
Formula C29H37Cl2N7O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 784210-87-3
Synonyms RGB286638, RGB 286638
SMILES COCCN1CCN(CC1)CC2=CC=C(C=C2)C3=NNC4=C3C(=O)C5=C4C=CC=C5NC(=O)NN6CCOCC6.Cl.Cl

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