RGD-4C

Catalog No.: A57411
αv-integrin Ligand
RGD-4C is a peptide characterized by the arginine-glycine-aspartic acid (ACDCRGDCFC) sequence, which specifically targets αv-integrins. This peptide's RGD motif mimics the binding sites of extracellular matrix proteins, facilitating interactions with integrins. RGD-4C serves as a valuable tool in research focused on cell adhesion, migration, and signaling, particularly in antitumor studies where it can be conjugated with bioactive molecules to enhance therapeutic efficacy in animal models.
Grouped product items
Size Price Stock Qty
5mg
$180.00
In stock
10mg
$295.00
In stock
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRGD-4C is a peptide characterized by the arginine-glycine-aspartic acid (ACDCRGDCFC) sequence, which specifically targets αv-integrins. This peptide's RGD motif mimics the binding sites of extracellular matrix proteins, facilitating interactions with integrins. RGD-4C serves as a valuable tool in research focused on cell adhesion, migration, and signaling, particularly in antitumor studies where it can be conjugated with bioactive molecules to enhance therapeutic efficacy in animal models.
Product Information
Catalog NumA57411
FormulaC42H60N14O16S4
Molecular Weight1145.27
CAS Number332179-76-7
Sequence shorteningACDCRGDCFCG(Disulfide bridge: Cys2-Cys10; Cys4-Cys8)
SMILES[H][C@]12CSSC[C@]([H])(NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](CC(O)=O)C(=O)N2)C(=O)NCC(O)=O
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