RH01504

Catalog No.: A75578
HIF2α Inhibitor
RH01504 is a potent inhibitor of HIF2α, exhibiting a Kd value of 5.42 nM against human HIF2α. This compound effectively suppresses the proliferation of renal cancer cells, making it a valuable tool for investigating renal cell carcinoma. RH01504 is applicable in research exploring the molecular mechanisms underlying hypoxia-driven tumor progression and offers potential insights into therapeutic strategies targeting HIF2α in cancer treatments.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRH01504 is a potent inhibitor of HIF2α, exhibiting a Kd value of 5.42 nM against human HIF2α. This compound effectively suppresses the proliferation of renal cancer cells, making it a valuable tool for investigating renal cell carcinoma. RH01504 is applicable in research exploring the molecular mechanisms underlying hypoxia-driven tumor progression and offers potential insights into therapeutic strategies targeting HIF2α in cancer treatments.
Product Information
Catalog NumA75578
FormulaC14H12ClNO3
Molecular Weight277.70
CAS Number301335-35-3
SMILESCOC1=CC(C(C2=C(C=CC(Cl)=C2)N)=O)=CC=C1O
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