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| Description | RITA, also referred to as NSC 652287, is a trycyclic thiophene derivative that binds to MDM2, disrupting the MDM2-p53 complex and subsequently activating p53 and inducing apoptosis. | |||||
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| Targets |
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| Cell Research |
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| Catalog Num | A11931 |
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| Formula | C14H12O3S2 |
| Molecular Weight | 292.4 |
| CAS Number | 213261-59-7 |
| SMILES | C1=C(SC(=C1)C2=CC=C(O2)C3=CC=C(S3)CO)CO |
| Synonyms | NSC652287, p53 Activator III |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 56 mg/mL (191.53 mM) | |
| Water | Insoluble | ||
| Ethanol | 8 mg/mL (27.36 mM) | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.2 mL | 171 mL | 342 mL |
| 0.5 mM | 6.84 mL | 34.2 mL | 68.4 mL |
| 1 mM | 3.42 mL | 17.1 mL | 34.2 mL |
| 5 mM | 0.68 mL | 3.42 mL | 6.84 mL |
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
