RITA (NSC 652287)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | RITA, also referred to as NSC 652287, is a trycyclic thiophene derivative that binds to MDM2, disrupting the MDM2-p53 complex and subsequently activating p53 and inducing apoptosis. | ||
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Catalog Num | A11931 |
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Formula | C14H12O3S2 |
Molecular Weight | 292.4 |
CAS Number | 213261-59-7 |
SMILES | C1=C(SC(=C1)C2=CC=C(O2)C3=CC=C(S3)CO)CO |
Synonyms | NSC652287, p53 Activator III |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 56 mg/mL (191.53 mM) | |
Water | Insoluble | ||
Ethanol | 8 mg/mL (27.36 mM) | ||
In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 34.2 mL | 171 mL | 342 mL |
0.5 mM | 6.84 mL | 34.2 mL | 68.4 mL |
1 mM | 3.42 mL | 17.1 mL | 34.2 mL |
5 mM | 0.68 mL | 3.42 mL | 6.84 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2