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Biological Activity
Rivanicline oxalate (RJR-2403 oxalate; (E)-Metanicotine oxalate) is a neuronal nicotinic receptor agonist, showing high selectivity for the α4β2 subtype (Ki=26 nM); > 1,000 fold selectivity than α7 receptors(Ki= 3.6 μM).
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 39.64 mL | 198.2 mL | 396.4 mL |
0.5 mM | 7.93 mL | 39.64 mL | 79.28 mL |
1 mM | 3.96 mL | 19.82 mL | 39.64 mL |
5 mM | 0.79 mL | 3.96 mL | 7.93 mL |
*The above data is based on the productmolecular weight 252.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A11544 |
---|---|
Actions | Agonist |
CAS No. | 220662-95-3 |
Formula | C12H16N2O4 |
M. Wt | 252.27 |
Purity | >98% |
Synonyms | RJR-2403 oxalate; (E)-Metanicotine oxalate |
SMILES | CNCC/C=C/C1=CC=CN=C1.OC(C(O)=O)=O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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