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RO 25-6981 maleate

NMDA receptors blocker

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Catalog No. A16083

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
RO 25-6981 maleate 5mg A16083-5
$70.00
RO 25-6981 maleate 10mg A16083-10
$120.00
RO 25-6981 maleate 50mg A16083-50
$480.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Ro 25-6981 Maleate is a potent and selective activity-dependent blocker of NMDA receptors containing the NR2B subunit. IC50 values are 0.009 and 52 uM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A respectively.

RO 25-6981 maleate

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Chemical Information

Catalog Num A16083
Actions Blocker
M. Wt 455.54
Formula C26H33NO6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1312991-76-6
Synonyms Ro25-6981
SMILES OC1=CC=C([[email protected]@H](O)[[email protected]@H](C)CN2CCC(CC3=CC=CC=C3)CC2)C=C1.O=C(O)/C=C\C(O)=O

Biological Activity

Description
Ro 25-6981 Maleate is a potent and selective activity-dependent blocker of NMDA receptors containing the NR2B subunit. IC50 values are 0.009 and 52 uM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A respectively.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.95 mL 109.76 mL 219.52mL
0.5 mM 4.39 mL 21.95 mL 43.9 mL
1 mM 2.2 mL 10.98 mL 21.95 mL
5 mM 0.44 mL 2.2 mL 4.39 mL

*The above data is based on the productmolecular weight 455.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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