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Ro 25-6981 Maleate is a potent and selective activity-dependent blocker of NMDA receptors containing the NR2B subunit. IC50 values are 0.009 and 52 uM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.95 mL | 109.76 mL | 219.52 mL |
| 0.5 mM | 4.39 mL | 21.95 mL | 43.9 mL |
| 1 mM | 2.2 mL | 10.98 mL | 21.95 mL |
| 5 mM | 0.44 mL | 2.2 mL | 4.39 mL |
*The above data is based on the productmolecular weight 455.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16083 |
|---|---|
| Actions | Blocker |
| M. Wt | 455.54 |
| Formula | C26H33NO6 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1312991-76-6 |
| Synonyms | Ro25-6981 |
| SMILES | OC1=CC=C([[email protected]@H](O)[[email protected]@H](C)CN2CCC(CC3=CC=CC=C3)CC2)C=C1.O=C(O)/C=C\C(O)=O |
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