Ro 31-8220

Catalog No.: A21765

PKC inhibitor

Ro 31-8220

Ro 31-8220 Chemical Structure

CAS NO. 125314-64-9

Ro 31-8220 is a potent PKC inhibitor, with IC50s of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

Ro 31-8220 is a potent PKC inhibitor, with IC50s of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.86 mL 109.28 mL 218.56 mL
0.5 mM 4.37 mL 21.86 mL 43.71 mL
1 mM 2.19 mL 10.93 mL 21.86 mL
5 mM 0.44 mL 2.19 mL 4.37 mL

*The above data is based on the productmolecular weight 457.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21765
Actions Inhibitor
M. Wt 457.55
Formula C25H23N5O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 125314-64-9
Synonyms Bisindolylmaleimide IX, Ro31-8220, Ro-31-8220
SMILES NC(SCCCN1C=C(C2=C(C3=CN(C)C4=C3C=CC=C4)C(NC2=O)=O)C5=C1C=CC=C5)=N

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