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$0.00 Biological Activity
Ro 3306 is an ATP-competitive, potent cyclin-dependent kinase (cdk) 1 inhibitor (Ki values are 35 and 110 nM for cdk1/cyclin B1 and cdk1/cyclin A respectively).
Targets
| Target | Value |
|---|---|
| CDK1 | ki: 20nM |
| PKCδ | ki: 318nM |
| SGK | ki: 497nM |
| ERK | ki: 1980nM |
| PKA | ki: >2000nM |
| Akt | ki: >2000nM |
| PKCα | ki: >2000nM |
| Fyn | ki: >2000nM |
| EphB3 | ki: >2000nM |
| In vitro | DMSO | Warmed: 12 mg/mL (34.14 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.45 mL | 142.27 mL | 284.54 mL |
| 0.5 mM | 5.69 mL | 28.45 mL | 56.91 mL |
| 1 mM | 2.85 mL | 14.23 mL | 28.45 mL |
| 5 mM | 0.57 mL | 2.85 mL | 5.69 mL |
*The above data is based on the productmolecular weight 351.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14437 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 872573-93-8 |
| Formula | C18H13N3OS2 |
| M. Wt | 351.45 |
| Purity | >98% |
| Synonyms | Ro3306, Ro-3306 |
| SMILES | C1=CC2=C(C=CC(=C2)/C=C/3\C(=O)N=C(S3)NCC4=CC=CS4)N=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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