Ro 3306

Catalog No.: A14437

CDK1 inhibitor

Ro 3306

Ro 3306 Chemical Structure

CAS NO. 872573-93-8

Ro 3306 is an ATP-competitive, potent cyclin-dependent kinase (cdk) 1 inhibitor (Ki values are 35 and 110 nM for cdk1/cyclin B1 and cdk1/cyclin A respectively).

Availability: In stock

Package Price Qty
10 mg

Regular Price: $100.00

Special Price $90.00

25 mg

Regular Price: $180.00

Special Price $162.00

50 mg

Regular Price: $300.00

Special Price $270.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Ro 3306 is an ATP-competitive, potent cyclin-dependent kinase (cdk) 1 inhibitor (Ki values are 35 and 110 nM for cdk1/cyclin B1 and cdk1/cyclin A respectively).
Targets
Target Value
CDK1ki: 20nM
PKCδki: 318nM
SGKki: 497nM
ERKki: 1980nM
PKAki: >2000nM
Aktki: >2000nM
PKCαki: >2000nM
Fynki: >2000nM
EphB3ki: >2000nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.45 mL 142.27 mL 284.54 mL
0.5 mM 5.69 mL 28.45 mL 56.91 mL
1 mM 2.85 mL 14.23 mL 28.45 mL
5 mM 0.57 mL 2.85 mL 5.69 mL

*The above data is based on the productmolecular weight 351.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A14437
Actions Inhibitor
M. Wt 351.45
Formula C18H13N3OS2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 872573-93-8
Synonyms Ro3306, Ro-3306
SMILES C1=CC2=C(C=CC(=C2)/C=C/3\C(=O)N=C(S3)NCC4=CC=CS4)N=C1

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