Ro 3306

Catalog No.: A14437

CDK1 inhibitor

Ro 3306

Ro 3306 Chemical Structure

CAS NO. 872573-93-8

Ro 3306 is an ATP-competitive, potent cyclin-dependent kinase (cdk) 1 inhibitor (Ki values are 35 and 110 nM for cdk1/cyclin B1 and cdk1/cyclin A respectively).

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10 mg

Regular Price: $100.00

Special Price $80.00

25 mg

Regular Price: $180.00

Special Price $144.00

50 mg

Regular Price: $300.00

Special Price $240.00

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Biological Activity

Ro 3306 is an ATP-competitive, potent cyclin-dependent kinase (cdk) 1 inhibitor (Ki values are 35 and 110 nM for cdk1/cyclin B1 and cdk1/cyclin A respectively).
Targets
Target Value
CDK1ki: 20nM
PKCδki: 318nM
SGKki: 497nM
ERKki: 1980nM
PKAki: >2000nM
Aktki: >2000nM
PKCαki: >2000nM
Fynki: >2000nM
EphB3ki: >2000nM
In vitro DMSO Warmed: 12 mg/mL (34.14 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.45 mL 142.27 mL 284.54 mL
0.5 mM 5.69 mL 28.45 mL 56.91 mL
1 mM 2.85 mL 14.23 mL 28.45 mL
5 mM 0.57 mL 2.85 mL 5.69 mL

*The above data is based on the productmolecular weight 351.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14437
Actions Inhibitor
CAS No. 872573-93-8
Formula C18H13N3OS2
M. Wt 351.45
Purity >98%
Synonyms Ro3306, Ro-3306
SMILES C1=CC2=C(C=CC(=C2)/C=C/3\C(=O)N=C(S3)NCC4=CC=CS4)N=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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