Ro 41-5253 is a selective antagonist of the retinoic acid receptor alpha (RARα). It effectively binds to RARα without promoting transcriptional activity or influencing RAR/RXR heterodimerization and DNA binding. This compound demonstrates significant inhibition of cancer cell proliferation and can induce apoptosis, highlighting its potential as an antitumor agent in cancer research applications.
Ro 41-5253 is a selective antagonist of the retinoic acid receptor alpha (RARα). It effectively binds to RARα without promoting transcriptional activity or influencing RAR/RXR heterodimerization and DNA binding. This compound demonstrates significant inhibition of cancer cell proliferation and can induce apoptosis, highlighting its potential as an antitumor agent in cancer research applications.
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