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|Storage||at -20°C 3 years Powder|
|Synonyms||Ro 488071, Ro488071|
|Chemical Name||[4??-[6-(Allylmethylamino)hexyloxy]-4-bromo-2??-fluorobenzophenone fumarate (1:1)|
|Ro 48-8071 inhibits cholesterol biosynthesis at the level of 2,3-oxidosqualene cyclase (OSC). It blocks OSC and cholesterol synthesis in HepG2 cells in the nanomolar range. A novel lipid lowering agent.|
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||17.72 mL||88.59 mL||177.18mL|
|0.5 mM||3.54 mL||17.72 mL||35.44 mL|
|1 mM||1.77 mL||8.86 mL||17.72 mL|
|5 mM||0.35 mL||1.77 mL||3.54 mL|
*The above data is based on the productmolecular weight 564.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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