RO 4938581

Name: RO 4938581
Brand: Adooq Bioscience
SKU: A20022
Rating: 5 (288 reviews)

Catalog No.: A20022

GABAA α5 inverse agonist

RO 4938581 is a potent and selective GABAA α5 inverse agonist, with a Ki of 4.6 nM for GABAA α5β3γ2a, and shows a lower affinity at α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki, 174, 185, 80 nM, respectively).

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RO 4938581 883093-10-5 GABAA α5 inverse agonist

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Grouped product items
Size	Price	Stock
1mg	$315.00	In stock
5mg	$360.00	In stock
10mg	$625.00	In stock
25mg	$1,225.00	In stock
50mg	$1,605.00	In stock
100mg	$2,645.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description	RO 4938581 is a potent and selective GABAA α5 inverse agonist, with a Ki of 4.6 nM for GABAA α5β3γ2a, and shows a lower affinity at α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki, 174, 185, 80 nM, respectively).

Product Information

Catalog Num	A20022
Formula	C13H8BrF2N5
Molecular Weight	352.14
CAS Number	883093-10-5
SMILES	FC(C1=C2N(C3=CC=C(Br)C=C3C4=NC=NN4C2)C=N1)F
Synonyms	RO-4938581, RO4938581
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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