RS-127445

Catalog No.: A11165

5-HT2B receptor antagonist

RS-127445

RS-127445 Chemical Structure

CAS NO. 199864-87-4

RS-127445 is a potent and selective antagonist at the serotonin 5-HT2B receptor, with around 1000x selectivity over the closely related 5-HT2A and 5-HT2C receptors.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $40.00

Special Price $36.00

10 mg

Regular Price: $70.00

Special Price $63.00

50 mg

Regular Price: $200.00

Special Price $180.00

100 mg

Regular Price: $320.00

Special Price $288.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

RS-127445 is a potent and selective antagonist at the serotonin 5-HT2B receptor, with around 1000x selectivity over the closely related 5-HT2A and 5-HT2C receptors.

Targets
5-HT2B 5-HT2B
10.4(pIC50)9.5(pKi)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.55 mL 177.73 mL 355.45 mL
0.5 mM 7.11 mL 35.55 mL 71.09 mL
1 mM 3.55 mL 17.77 mL 35.55 mL
5 mM 0.71 mL 3.55 mL 7.11 mL

*The above data is based on the productmolecular weight 281.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A11165
Actions Antagonist
M. Wt 281.33
Formula C17H16FN3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 199864-87-4
Synonyms RS127445, MT 500, RS127,445
SMILES CC(C)C1=NC(=NC(=C1)C2=CC=C(C3=CC=CC=C32)F)N.Cl

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy RS-127445 | RS-127445 Supplier | purchase RS-127445 | RS-127445 cost | RS-127445 manufacturer | order RS-127445 | RS-127445 distributor | buy 199864-87-4| 199864-87-4 Supplier | purchase 199864-87-4 | 199864-87-4 cost | 199864-87-4 manufacturer | order 199864-87-4 | 199864-87-4 distributor
Rewards