RSV/IAV-IN-3 is a dual inhibitor targeting both respiratory syncytial virus (RSV) and influenza A virus (IAV) with reported EC50 values of 2.92 µM and 1.90 µM, respectively. This compound exhibits significant antiviral activity against H1N1 and H3N2 strains, achieving EC50 values of 3.25 µM and 1.50 µM in MDCK cells. Notably, RSV/IAV-IN-3 inhibits IAV infectivity and RNA-dependent RNA polymerase (RdRp) activity while effectively suppressing viral replication at the post-entry stage. Its influence on luciferase activity further emphasizes its potential in antiviral research applications.
RSV/IAV-IN-3 is a dual inhibitor targeting both respiratory syncytial virus (RSV) and influenza A virus (IAV) with reported EC50 values of 2.92 µM and 1.90 µM, respectively. This compound exhibits significant antiviral activity against H1N1 and H3N2 strains, achieving EC50 values of 3.25 µM and 1.50 µM in MDCK cells. Notably, RSV/IAV-IN-3 inhibits IAV infectivity and RNA-dependent RNA polymerase (RdRp) activity while effectively suppressing viral replication at the post-entry stage. Its influence on luciferase activity further emphasizes its potential in antiviral research applications.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
