RSV-IN-5 is a potent dual inhibitor targeting respiratory syncytial virus (RSV) fusion proteins, effective against both wild-type and mutant strains. This compound demonstrates significant anti-RSV activity, with an EC50 of 2.0 nM against the wild-type A2 F protein and 8.1 nM against the D486N-mutant F protein. Its efficacy makes RSV-IN-5 a valuable tool in research focused on RSV-related therapeutics and understanding viral resistance mechanisms.
RSV-IN-5 is a potent dual inhibitor targeting respiratory syncytial virus (RSV) fusion proteins, effective against both wild-type and mutant strains. This compound demonstrates significant anti-RSV activity, with an EC50 of 2.0 nM against the wild-type A2 F protein and 8.1 nM against the D486N-mutant F protein. Its efficacy makes RSV-IN-5 a valuable tool in research focused on RSV-related therapeutics and understanding viral resistance mechanisms.
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