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RU 26752

Catalog No.: A76663
Mineralocorticoid Receptor Antagonists
RU 26752 is a mineralocorticoid receptor antagonist that modulates the activity of steroid hormone receptors. It effectively inhibits hypertension induced by aldosterone in preclinical models, making it a valuable tool for studying cardiovascular diseases and related conditions. This compound is useful for researchers investigating the role of mineralocorticoid receptors in hypertension and its pathophysiological mechanisms.
RU 26752 76676-33-0 Mineralocorticoid Receptor Antagonists
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRU 26752 is a mineralocorticoid receptor antagonist that modulates the activity of steroid hormone receptors. It effectively inhibits hypertension induced by aldosterone in preclinical models, making it a valuable tool for studying cardiovascular diseases and related conditions. This compound is useful for researchers investigating the role of mineralocorticoid receptors in hypertension and its pathophysiological mechanisms.
Product Information
Catalog NumA76663
FormulaC25H36O3
Molecular Weight384.55
CAS Number76676-33-0
SMILESC[C@@]12[C@@]3(OC(CC3)=O)CC[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H]4CCC)=CC(CC5)=O)C)([H])CC2
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Endocrinology-Hormones > Mineralocorticoid Receptor