RU-TRAAK-2 is a selective inhibitor of the TRAAK (TWIK-related arachidonic acid-stimulated K+ channel) that demonstrates complete reversibility in its inhibitory action. It shows no activity against other potassium channels, including Kv1.2, Slo1, and GIRK2, ensuring specificity in experimental applications. Additionally, RU-TRAAK-2 features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions, making it a valuable tool in chemical biology for labeling and tagging biomolecules. This compound is primarily utilized in research focusing on ion channel regulation and signaling pathways.
RU-TRAAK-2 is a selective inhibitor of the TRAAK (TWIK-related arachidonic acid-stimulated K+ channel) that demonstrates complete reversibility in its inhibitory action. It shows no activity against other potassium channels, including Kv1.2, Slo1, and GIRK2, ensuring specificity in experimental applications. Additionally, RU-TRAAK-2 features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions, making it a valuable tool in chemical biology for labeling and tagging biomolecules. This compound is primarily utilized in research focusing on ion channel regulation and signaling pathways.
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