Rubitecan
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | Rubitecan (RFS 2000), a Camptothecin derivative, is an orally active topoisomerase I inhibitor with broad antitumor activity, and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells. |
---|
Catalog Num | A22040 |
---|---|
Formula | C20H15N3O6 |
Molecular Weight | 393.35 |
CAS Number | 91421-42-0 |
SMILES | O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C([N+]([O-])=O)C=CC=C5N=C4C3=C2)=O |
Synonyms | RFS 2000, RFS2000, RFS-2000; 9-Nitrocamptothecin |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 51 mg/mL (129.65 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.42 mL | 127.11 mL | 254.23 mL |
0.5 mM | 5.08 mL | 25.42 mL | 50.85 mL |
1 mM | 2.54 mL | 12.71 mL | 25.42 mL |
5 mM | 0.51 mL | 2.54 mL | 5.08 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2