(S)-Deoxy-thalidomide-(R)-pyrrolidine-3-carbaldehyde is an E3 ligase ligand-linker conjugate featuring a CRBN-based ligand. This compound is instrumental in the synthesis of proteolysis-targeting chimeras (PROTACs), facilitating targeted degradation of specific proteins within cellular systems. Its unique structure enables efficient recruitment of E3 ligases, making it essential for studies in targeted protein degradation and drug development.
(S)-Deoxy-thalidomide-(R)-pyrrolidine-3-carbaldehyde is an E3 ligase ligand-linker conjugate featuring a CRBN-based ligand. This compound is instrumental in the synthesis of proteolysis-targeting chimeras (PROTACs), facilitating targeted degradation of specific proteins within cellular systems. Its unique structure enables efficient recruitment of E3 ligases, making it essential for studies in targeted protein degradation and drug development.
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