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Biological Activity
(S)-JQ-35 (TEN-010) is an inhibitor of the Bromodomain and Extra-Terminal (BET) family bromodomain-containing proteins with potential antineoplastic activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.51 mL | 92.57 mL | 185.14 mL |
| 0.5 mM | 3.7 mL | 18.51 mL | 37.03 mL |
| 1 mM | 1.85 mL | 9.26 mL | 18.51 mL |
| 5 mM | 0.37 mL | 1.85 mL | 3.7 mL |
*The above data is based on the productmolecular weight 540.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18730 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1349719-98-7 |
| Formula | C27H34ClN7OS |
| M. Wt | 540.12 |
| Purity | >98% |
| Synonyms | JQ-35, (S)-; Bet inhibitor TEN-010; (S)-JQ35; |
| SMILES | O=C(NCCCN1CCN(C)CC1)C[C@H]2C3=NN=C(C)N3C4=C(C(C)=C(C)S4)C(C5=CC=C(Cl)C=C5)=N2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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