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(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH

Catalog No.: A80175
E3 Ligase Ligand-Linker Conjugate
(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH is an E3 ligase ligand-linker conjugate featuring a VHL ligand. This compound is utilized in PROTAC (Proteolysis Targeting Chimeras) technology, which enables targeted protein degradation. Its design facilitates selective degradation of specific proteins, making it a valuable tool for studying protein function and developing therapeutic strategies in various diseases.
(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH 2086301-47-3 E3 Ligase Ligand-Linker Conjugate
Grouped product items
Size Price Stock Qty
5mg
$260.00
In stock
10mg
$435.00
In stock
25mg
$835.00
In stock
50mg
$1,435.00
In stock
100mg
$2,240.00
In stock
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH is an E3 ligase ligand-linker conjugate featuring a VHL ligand. This compound is utilized in PROTAC (Proteolysis Targeting Chimeras) technology, which enables targeted protein degradation. Its design facilitates selective degradation of specific proteins, making it a valuable tool for studying protein function and developing therapeutic strategies in various diseases.
Product Information
Catalog NumA80175
FormulaC39H58N6O7S
Molecular Weight754.98
CAS Number2086301-47-3
SMILESO=C(CN1CCC(O[C@H]2C[C@H](NC(OC(C)(C)C)=O)C2)CC1)N[C@H](C(N([C@H](C(N[C@@H](C)C3=CC=C(C=C3)C4=C(C)N=CS4)=O)C5)C[C@@H]5O)=O)C(C)(C)C
SynonymsVH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH
Useful Calculator

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PROTAC > E3 Ligase Ligand-Linker Conjugate