(S,R,S)-AHPC-C1-Br is a synthetic E3 ligase ligand-linker conjugate that utilizes the (S,R,S)-AHPC-based VHL ligand along with a specialized linker for targeted protein degradation applications. This compound is essential for research involving proteolysis-targeting chimeras (PROTACs), facilitating the selective degradation of specific proteins through the ubiquitin-proteasome system. Its design enhances the engagement and modulation of E3 ligases, contributing to advancements in therapeutic strategies targeting various diseases.
(S,R,S)-AHPC-C1-Br is a synthetic E3 ligase ligand-linker conjugate that utilizes the (S,R,S)-AHPC-based VHL ligand along with a specialized linker for targeted protein degradation applications. This compound is essential for research involving proteolysis-targeting chimeras (PROTACs), facilitating the selective degradation of specific proteins through the ubiquitin-proteasome system. Its design enhances the engagement and modulation of E3 ligases, contributing to advancements in therapeutic strategies targeting various diseases.
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