(S,R,S)-AHPC-C3-COOH

Catalog No.: A80240
Vhl Ligand-Linker Conjugate
(S,R,S)-AHPC-C3-COOH is a carboxylic acid derivative targeting the VHL E3 ubiquitin ligase, functioning as a ligand-linker conjugate. This compound is instrumental in the synthesis of PROTACs (Proteolysis Targeting Chimeras), facilitating targeted protein degradation for potential therapeutic applications. Its structural properties make it a valuable tool in chemical biology for exploring ubiquitin-mediated proteolysis and developing innovative strategies in drug discovery.
Grouped product items
Size Price Stock Qty
25mg
$55.00
In stock
50mg
$110.00
In stock
100mg
$160.00
In stock
250mg
$265.00
In stock
500mg
$435.00
In stock
1g
$785.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(S,R,S)-AHPC-C3-COOH is a carboxylic acid derivative targeting the VHL E3 ubiquitin ligase, functioning as a ligand-linker conjugate. This compound is instrumental in the synthesis of PROTACs (Proteolysis Targeting Chimeras), facilitating targeted protein degradation for potential therapeutic applications. Its structural properties make it a valuable tool in chemical biology for exploring ubiquitin-mediated proteolysis and developing innovative strategies in drug discovery.
Product Information
Catalog NumA80240
FormulaC27H36N4O6S
Molecular Weight544.66
CAS Number2172819-73-5
SMILESOC(CCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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