(S,R,S)-AHPC-C5-NH2 dihydrochloride is an E3 ligase ligand-linker conjugate that features a VH032-derived VHL ligand coupled with a linker designed for estrogen-related receptor α (ERRα) PROTAC degradation. This compound facilitates targeted protein degradation through specific ubiquitination of ERRα, making it a valuable tool for research applications involving synthetic biology and therapeutic interventions in hormone-related pathways. Its design enhances the efficiency of targeted protein degradation processes, providing researchers with a potent means of modulating protein levels in cellular systems.
(S,R,S)-AHPC-C5-NH2 dihydrochloride is an E3 ligase ligand-linker conjugate that features a VH032-derived VHL ligand coupled with a linker designed for estrogen-related receptor α (ERRα) PROTAC degradation. This compound facilitates targeted protein degradation through specific ubiquitination of ERRα, making it a valuable tool for research applications involving synthetic biology and therapeutic interventions in hormone-related pathways. Its design enhances the efficiency of targeted protein degradation processes, providing researchers with a potent means of modulating protein levels in cellular systems.
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