(S,R,S)-AHPC-C5-NH2 is an E3 ligase ligand-linker conjugate designed for targeted protein degradation applications. It combines a VH032-derived VHL ligand with a linker specifically for the estrogen-related receptor α (ERRα) PROTAC system. This compound facilitates the formation of complex structures that promote the ubiquitination and subsequent degradation of ERRα, thereby enabling in-depth studies on its biological functions and potential therapeutic interventions.
(S,R,S)-AHPC-C5-NH2 is an E3 ligase ligand-linker conjugate designed for targeted protein degradation applications. It combines a VH032-derived VHL ligand with a linker specifically for the estrogen-related receptor α (ERRα) PROTAC system. This compound facilitates the formation of complex structures that promote the ubiquitination and subsequent degradation of ERRα, thereby enabling in-depth studies on its biological functions and potential therapeutic interventions.
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